The singer, 29, who is pregnant, and the producer, 31, exchanged vows in front of close family and friends in a private home on the Mediterranean Sea.
Their friend Dr. Deepak Chopra presided over the intimate ceremony.
Keys wore an ivory silk, georgette-draped Vera Wang goddess gown with jewel detail on the back shoulder.
She carried a bouquet of purple calla lilies. The groom donned a classic Tom Ford tuxedo.
"Wowwwwwwwwww," Beatz (real name: Kasseem Dean) Twittered Saturday. He later wrote, "It's a brand new day :) I feel like Nas and Diddy song :) love y’all and blessing!"